Movement related dynamics of subthalmo-cortical alpha connectivity in Parkinson's disease.

ABSTRACT: Functional neurosurgical techniques provide a unique opportunity to explore patterns of interaction between the cerebral cortex and basal ganglia in patients with Parkinson's disease (PD). Previous work using simultaneous magnetoencephalographic (MEG) and local field potential (LFP) recordings from the region of the subthalamic nucleus (STNr) has characterised resting patterns of connectivity in the alpha and beta frequency bands and their modulation by dopaminergic medication. Recently we have also characterised the effect of movement on patterns of gamma band coherence between the STNr and cortical sites. Here we specifically investigate how the prominent coherence between the STNr and temporal cortex in the alpha band is modulated by movement both on and off dopaminergic medication in p

SUBMITTER: Oswal A 

PROVIDER: S-EPMC3591253 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature