Gene expression analysis of copper tolerance and wood decay in the brown rot fungus Fibroporia radiculosa.

ABSTRACT: High-throughput transcriptomics was used to identify Fibroporia radiculosa genes that were differentially regulated during colonization of wood treated with a copper-based preservative. The transcriptome was profiled at two time points while the fungus was growing on wood treated with micronized copper quat (MCQ). A total of 917 transcripts were differentially expressed. Fifty-eight of these genes were more highly expressed when the MCQ was protecting the wood from strength loss and had putative functions related to oxalate production/degradation, laccase activity, quinone biosynthesis, pectin degradation, ATP production, cytochrome P450 activity, signal transduction, and transcriptional regulation. Sixty-one genes were more highly expressed when the MCQ lost its effectiveness (>50% streng

SUBMITTER: Tang JD 

PROVIDER: S-EPMC3591939 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature