Similar patterns of infection with bovine foamy virus in experimentally inoculated calves and sheep.

ABSTRACT: Foamy viruses (FVs) are the least known retroviruses commonly found in primates, cats, horses, and cattle. Although FVs are considered apathogenic, simian and feline FVs have been shown to be associated with some transient health abnormalities in animal models. Currently, data regarding the course of infection with bovine FV (BFV) are not available. In this study, we conducted experimental infections of natural (cattle) and heterologous (sheep) hosts with the BFV(100) isolate and monitored infection patterns in both hosts during the early phase postinoculation as well as after long-term infection. Four calves and six sheep inoculated with BFV(100) showed no signs of pathology but developed persistent infection, as confirmed by virus rescue, consistent detection of BFV-specific antibodies,

SUBMITTER: Materniak M 

PROVIDER: S-EPMC3592159 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature