Confirming glycemic status in the Diabetes Prevention Program: implications for diagnosing diabetes in high risk adults.

ABSTRACT:

Aims

To examine the ability of fasting plasma glucose (FPG) and/or 2-h glucose to confirm diabetes and to determine the proportion of participants with HbA1c ≥6.5%.

Methods

Diabetes confirmation rates were calculated after a single elevated FPG and/or 2-h glucose on an oral glucose tolerance test (OGTT) using a confirmatory OGTT performed within 6 weeks.

Results

772 (24%) participants had elevated FPG or 2-h glucose on an OGTT that triggered a confirmation visit. There were 101 triggers on FPG alone, 574 on 2-h glucose alone, and 97 on both. Only 47% of participants who triggered had confirmed diabetes. While the confirmation rate for FPG was higher than that for 2-h glucose, the larger number of 2-h glucose triggers resulted in 87% of confirmed cases triggering on 2-

SUBMITTER: Christophi CA 

PROVIDER: S-EPMC3594066 | biostudies-literature | 2013 Mar-Apr

REPOSITORIES: biostudies-literature