The association between mucin balls and corneal infiltrative events during extended contact lens wear.

ABSTRACT:

Purpose

To determine the association between mucin ball formation and corneal infiltrative events (CIEs) during continuous wear with lotrafilcon A silicone hydrogel contact lenses.

Methods

Subjects (n = 205) in the Longitudinal Analysis of Silicone Hydrogel Contact Lens Study wore lotrafilcon A contact lenses for 12 months of continuous wear. The primary outcome was a CIE. Kaplan-Meier methods were used to estimate the unadjusted cumulative incidence of remaining CIE free stratified by mucin ball presence. Cox proportional hazards regression was used to model the hazard of developing a CIE as a function of mucin ball formation and other covariates.

Results

Over half (54.2%) of the subjects displayed some presence of mucin balls during at least 1 visit and about one th

SUBMITTER: Szczotka-Flynn L 

PROVIDER: S-EPMC3596007 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature