Antimullerian hormone levels are independently related to ovarian hyperandrogenism and polycystic ovaries.

ABSTRACT:

Objective

To determine the relationship of antimüllerian hormone (AMH) levels to polycystic ovaries and ovarian androgenic function.

Design

Prospective case-control study.

Setting

General clinical research center.

Participant(s)

Eumenorrheic asymptomatic volunteers without (V-NO; n = 19; reference population) or with (V-PCO; n = 28) a polycystic ovary and hyperandrogenemic anovulatory subjects grouped according to ovarian function into typical PCOS (PCOS-T; n = 37) and atypical PCOS (PCOS-A; n = 18).

Intervention(s)

Pelvic ultrasonography, short dexamethasone androgen-suppression test (SDAST), and GnRH agonist (GnRHag) test.

Main outcome measure(s)

Baseline AMH levels were related to polycystic ovary status, testosterone response to SDAST, and 17-

SUBMITTER: Rosenfield RL 

PROVIDER: S-EPMC3597099 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature