Protein molecular surface mapped at different geometrical resolutions.

ABSTRACT: Many areas of biochemistry and molecular biology, both fundamental and applications-orientated, require an accurate construction, representation and understanding of the protein molecular surface and its interaction with other, usually small, molecules. There are however many situations when the protein molecular surface gets in physical contact with larger objects, either biological, such as membranes, or artificial, such as nanoparticles. The contribution presents a methodology for describing and quantifying the molecular properties of proteins, by geometrical and physico-chemical mapping of the molecular surfaces, with several analytical relationships being proposed for molecular surface properties. The relevance of the molecular surface-derived properties has been demonstrated through

SUBMITTER: Nicolau DV 

PROVIDER: S-EPMC3597524 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature