A case of lipoprotein glomerulopathy with thrombotic microangiopathy due to malignant hypertension.

ABSTRACT:

Background

Lipoprotein glomerulopathy (LPG) is a rare inherited renal disease characterized by intraglomerular lipoprotein within the lumina of severely dilated glomerular capillaries. The common clinical presentation of LPG includes proteinuria or nephrotic syndrome. Hypertension and anemia were thought to be mild in LPG. Thrombotic microangiopathy (TMA) in LPG has not been previously reported. In this report, we present a patient with LPG that developed TMA. To the best of our knowledge, this is the first report of TMA in LPG.

Case presentation

Four years ago (2005), a 19-year-old Chinese woman was diagnosed with nephrotic syndrome and provided prednisone treatment. A combination of prednisone and cyclophosphamide did not have any effect and was discontinued after six mont

SUBMITTER: Wu Y 

PROVIDER: S-EPMC3598816 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature