Using a model filamentous fungus to unravel mechanisms of lignocellulose deconstruction.

ABSTRACT: Filamentous fungi are the main source of enzymes used to degrade lignocellulose to fermentable sugars for the production of biofuels. While the most commonly used organism for the production of cellulases in an industrial setting is Trichoderma reesei (Hypocrea jecorina), recent work in the model filamentous fungus Neurospora crassa has shown that the variety of molecular, genetic and biochemical techniques developed for this organism can expedite analyses of the complexities involved in the utilization of lignocellulose as a source of carbon. These include elucidating regulatory networks associated with plant cell wall deconstruction, the identification of signaling molecules necessary for induction of the expression of genes encoding lignocellulolytic enzymes and the characterization of

SUBMITTER: Znameroski EA 

PROVIDER: S-EPMC3598899 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature