Assessment of reproducibility of cancer survival risk predictions across medical centers.

ABSTRACT:

Background

Two most important considerations in evaluation of survival prediction models are 1) predictability - ability to predict survival risks accurately and 2) reproducibility - ability to generalize to predict samples generated from different studies. We present approaches for assessment of reproducibility of survival risk score predictions across medical centers.

Methods

Reproducibility was evaluated in terms of consistency and transferability. Consistency is the agreement of risk scores predicted between two centers. Transferability from one center to another center is the agreement of the risk scores of the second center predicted by each of the two centers. The transferability can be: 1) model transferability - whether a predictive model developed from one center c

SUBMITTER: Chen HC 

PROVIDER: S-EPMC3598915 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature