Cross-species transcriptional network analysis reveals conservation and variation in response to metal stress in cyanobacteria.

ABSTRACT:

Background

As one of the most dominant bacterial groups on Earth, cyanobacteria play a pivotal role in the global carbon cycling and the Earth atmosphere composition. Understanding their molecular responses to environmental perturbations has important scientific and environmental values. Since important biological processes or networks are often evolutionarily conserved, the cross-species transcriptional network analysis offers a useful strategy to decipher conserved and species-specific transcriptional mechanisms that cells utilize to deal with various biotic and abiotic disturbances, and it will eventually lead to a better understanding of associated adaptation and regulatory networks.

Results

In this study, the Weighted Gene Co-expression Network Analysis (WGCNA) approach

SUBMITTER: Wang J 

PROVIDER: S-EPMC3598940 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature