Identification of differences in microRNA transcriptomes between porcine oxidative and glycolytic skeletal muscles.

ABSTRACT:

Background

MicroRNAs (miRNAs) are a type of non-coding small RNA ~22 nucleotides in length that regulate the expression of protein coding genes at the post-transcriptional level. Glycolytic and oxidative myofibers, the two main types of skeletal muscles, play important roles in metabolic health as well as in meat quality and production in the pig industry. Previous expression profile studies of different skeletal muscle types have focused on these aspects of mRNA and proteins; nonetheless, an explanation of the miRNA transcriptome differences between these two distinct muscles types is long overdue.

Results

Herein, we present a comprehensive analysis of miRNA expression profiling between the porcine longissimus doris muscle (LDM) and psoas major muscle (PMM) using a deep seq

SUBMITTER: Liu Y 

PROVIDER: S-EPMC3599761 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature