18F-fluorodeoxyglucose positron emission tomography in the management of patients with thymic epithelial tumors.

ABSTRACT:

Purpose

There are limited data regarding the role of (18)F-fluorodeoxyglucose positron emission tomography ([(18)F]-FDG PET) imaging in management of patients with thymic epithelial tumors (TET). The primary objective of this study was to assess the usefulness of early [(18)F]-FDG PET to monitor treatment efficacy and its correlation with Response Evaluation Criteria in Solid Tumors (RECIST) in patients with TETs.

Experimental design

[(18)F]-FDG PET/computed tomographic (CT) scans were conducted at baseline and after 6 weeks of treatment in patients enrolled in two phase II and one phase I/II clinical trials. On the basis of data from other solid tumors, metabolic response was defined as a reduction of [(18)F]-FDG uptake by more than 30% as assessed by average standardized u

SUBMITTER: Thomas A 

PROVIDER: S-EPMC3602145 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature