Project description:This project investigates the mechanisms that underlie asthma-related phenotypes associated with allergen exposure. See http://www.hopkins-genomics.org/asthma/asthma006/index.html The goal of the experiment was to identify genes that change their levels of expression as a consequence of challenge with allergen. The experiments utilized a murine model of human asthma that employed BALB/CJ mice. In this particular sensitization-challenge protocol, the response produced by BALB/CJ mice is representative of a majority of the mouse strains tested. The antigen complex used to sensitize and challenge the mice was ragweed pollen an allergen that is highly relevant to human disease. Keywords: time series, allergen

2005-08-24 | GSE3184 | GEO

Human Airway Hyperresponsiveness

Project description:The purpose of this project is to gain a better understanding of the early cytokine-mediated mechanisms that lead to asthma. Keywords: time series, IL13

2005-08-24 | GSE3183 | GEO

Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness.

Project description: Not available

| S-EPMC2718465 | biostudies-literature