Lung cancer screening with computer aided detection chest radiography: design and results of a randomized, controlled trial.

ABSTRACT:

Introduction

The sensitivity of CT based lung cancer screening for the detection of early lung cancer is balanced by the high number of benign lung nodules identified, the unknown consequences of radiation from the test, and the potential costs of a CT based screening program. CAD chest radiography may improve the sensitivity of standard chest radiography while minimizing the risks of CT based screening.

Methods

Study subjects were age 40-75 years with 10+ pack-years of smoking and/or an additional risk for developing lung cancer. Subjects were randomized to receive a PA view chest radiograph or placebo control (went through the process of being imaged but were not imaged). Images were reviewed first without then with the assistance of CAD. Actionable nodules were reported a

SUBMITTER: Mazzone PJ 

PROVIDER: S-EPMC3603858 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature