Household mold and dust allergens: exposure, sensitization and childhood asthma morbidity.

ABSTRACT:

Background

Few studies address concurrent exposures to common household allergens, specific allergen sensitization and childhood asthma morbidity.

Objective

To identify levels of allergen exposures that trigger asthma exacerbations in sensitized individuals.

Methods

We sampled homes for common indoor allergens (fungi, dust mites (Der p 1, Der f 1), cat (Fel d 1), dog (Can f 1) and cockroach (Bla g 1)) for levels associated with respiratory responses among school-aged children with asthma (N=1233) in a month-long study. Blood samples for allergy testing and samples of airborne fungi and settled dust were collected at enrollment. Symptoms and medication use were recorded on calendars. Combined effects of specific allergen sensitization and level of exposure on wheeze, p

SUBMITTER: Gent JF 

PROVIDER: S-EPMC3604733 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature