Why is greater medication adherence associated with better outcomes.

ABSTRACT:

Background

Previous studies found an association of greater adherence to placebo medication with better outcomes. The present study tested whether this association was explained by any of the following factors: 1) adherence to other medications, 2) healthcare behaviors, 3) disease risk, or 4) predicted degree of adherence. Data included information on more than 800 risk factors from 27,347 subjects in two randomized controlled trials of hormone therapy in the Women's Health Initiative.

Results

Greater adherence to placebo was not associated with colon cancer but was substantially and significantly associated with several diverse outcomes: death, myocardial infarction, stroke, and breast cancer. Adherence to hormone therapy was only weakly associated with outcomes. The WHI ri

SUBMITTER: Hartz A 

PROVIDER: S-EPMC3605162 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature