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Home blood pressure variability as cardiovascular risk factor in the population of Ohasama.


ABSTRACT: Blood pressure variability based on office measurement predicts outcome in selected patients. We explored whether novel indices of blood pressure variability derived from the self-measured home blood pressure predicted outcome in a general population. We monitored mortality and stroke in 2421 Ohasama residents (Iwate Prefecture, Japan). At enrollment (1988-1995), participants (mean age, 58.6 years; 60.9% women; 27.1% treated) measured their blood pressure at home, using an oscillometric device. In multivariable-adjusted Cox models, we assessed the independent predictive value of the within-subject mean systolic blood pressure (SBP) and corresponding variability as estimated by variability independent of the mean, difference between maximum and minimum blood pressure, and average real varia

SUBMITTER: Asayama K 

PROVIDER: S-EPMC3607332 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature