Mapping analyses to estimate EQ-5D utilities and responses based on Oxford Knee Score.

ABSTRACT:

Purpose

The Oxford Knee Score (OKS) is a validated 12-item measure of knee replacement outcomes. An algorithm to estimate EQ-5D utilities from OKS would facilitate cost-utility analysis on studies analyses using OKS but not generic health state preference measures. We estimate mapping (or cross-walking) models that predict EQ-5D utilities and/or responses based on OKS. We also compare different model specifications and assess whether different datasets yield different mapping algorithms.

Methods

Models were estimated using data from the Knee Arthroplasty Trial and the UK Patient Reported Outcome Measures dataset, giving a combined estimation dataset of 134,269 questionnaires from 81,213 knee replacement patients and an internal validation dataset of 45,213 questionnaires fro

SUBMITTER: Dakin H 

PROVIDER: S-EPMC3607737 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature