"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site.

ABSTRACT: We have demonstrated the fabrication of "aligned-to-random" electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions.

SUBMITTER: Xie J 

PROVIDER: S-EPMC3609028 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature