Designing industrial yeasts for the consolidated bioprocessing of starchy biomass to ethanol.

ABSTRACT: Consolidated bioprocessing (CBP), which integrates enzyme production, saccharification and fermentation into a one step process, is a promising strategy for the effective ethanol production from cheap lignocellulosic and starchy materials. CBP requires a highly engineered microbial strain able to both hydrolyze biomass with enzymes produced on its own and convert the resulting simple sugars into high-titer ethanol. Recently, heterologous production of cellulose and starch-degrading enzymes has been achieved in yeast hosts, which has realized direct processing of biomass to ethanol. However, essentially all efforts aimed at the efficient heterologous expression of saccharolytic enzymes in yeast have involved laboratory strains and much of this work has to be transferred to industrial yeasts

SUBMITTER: Favaro L 

PROVIDER: S-EPMC3609629 | biostudies-literature | 2013 Mar-Apr

REPOSITORIES: biostudies-literature