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The Heart Failure Adherence and Retention Trial (HART): design and rationale.


ABSTRACT:

Background

Heart failure (HF) is increasing in prevalence and is associated with prolonged morbidity, repeat hospitalizations, and high costs. Drug therapies and lifestyle changes can reduce hospitalizations, but nonadherence is high, ranging from 30% to 80%. There is an urgent need to identify cost-effective ways to improve adherence and reduce hospitalizations.

Trial design

The Heart Failure Adherence and Retention Trial (HART) evaluated the benefit of patient self-management (SM) skills training in combination with HF education, over HF education alone, on the composite end points of death/HF hospitalizations and death/all-cause hospitalizations in patients with mild to moderate systolic or diastolic dysfunction. Secondary end points included progression of HF, quality of

SUBMITTER: Powell LH 

PROVIDER: S-EPMC3609705 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature