2-Seleno-1-alkylbenzimidazoles and their Diselenides: Synthesis and Structural Characterization of a 2-Seleno-1-methylbenzimidazole Complex of Mercury.

ABSTRACT: 2-Seleno-1-methylbenzimidazole, H(sebenzim^Me), can be synthesized from 1-methylbenzimidazole by sequential treatment with (i) BuⁿLi, (ii) elemental selenium and (iii) HCl(aq). This method is also applicable to the synthesis of 2-seleno-1-t-butylbenzimidazole, H(sebenzim^But ). Single crystal X-ray diffraction and NMR spectroscopic data demonstrate that H(sebenzim^Me) and H(sebenzim^But ) exist as the selone rather than the selenol tautomers, which is in accord with the results of density functional theory (B3LYP) calculations. The data also indicate that the selone is best represented as a C⁺-Se^- zwitterion rather than as a C=Se doubly bonded species. Aerobic oxidation of H(

SUBMITTER: Palmer JH 

PROVIDER: S-EPMC3610765 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature