Assessment of a multimarker strategy for prediction of mortality in older heart failure patients: a cohort study.

ABSTRACT: Primarily to develop a multimarker score for prediction of 3-year mortality in older patients with decompensated heart failure (HF). Prospective cohort study. Secondary care. Single centre. PATIENTS AND BIOMARKERS: 131 patients, aged ≥65 years, with decompensated HF were included. Assessment of biomarkers was performed at discharge. 3-year mortality. Mean age was 73±11 years; mean left ventricular ejection fraction , 43±14%; 53% were male. The 3-year mortality was 53.4%. The following N-terminal brain natriuretic peptide (NTproBNP) levels could optimally stratify mortality: <2000 ng/l (n=39), 30.8% mortality; 2000-8000 ng/l (n=58), 51.7% mortality; and >8000 ng/l (n=34), 82.4% mortality. However, in the 2000-8000 ng/l range, NTproBNP levels had low-prognostic capacity, based on the area un

SUBMITTER: Bjurman C 

PROVIDER: S-EPMC3612770 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature