Ontology highlight
ABSTRACT:
SUBMITTER: Liu FC
PROVIDER: S-EPMC3613066 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Liu Fon-Chang FC Pan Chun-Hsu CH Lai Ming-Tsung MT Chang Shu-Jen SJ Chung Jing-Gung JG Wu Chieh-Hsi CH
Evidence-based complementary and alternative medicine : eCAM 20130317
The aim of this study was to explore the antitumor effect of Gan-Lu-Yin (GLY), a traditional Chinese herbal formula, on leukemia. Ethanolic extract of GLY was applied to evaluate its regulatory mechanisms in proliferation, migration, and differentiation of WEHI-3 leukemic cells as well as antitumor effect on BALB/c mice model. The results showed that GLY markedly reduced cell proliferation and migration with induced differentiation of WEHI-3 cells. The expression level of phosphorylated FAK, Akt ...[more]