Low voltage picoliter droplet manipulation utilizing electrowetting-on-dielectric platforms.

ABSTRACT: Picoliter droplets actuated on an electrowetting-on-dielectric (EWD) actuator are demonstrated. In this study, the physical scaling of electrodes for 33 μm and 21 μm EWD devices resulted in droplets of 12 pl and 5 pl being dispensed respectively in conjunction with 3 μm SU8 gaskets. The stacked multi-layer insulators in the actuators consisted of 200 nm tantalum pentoxide (Ta₂O₅) and 200 nm parylene C films deposited and coated with 70 nm of CYTOP. The voltages for dispensing droplets on chips without any external pressure sources are 17.1 V_rms and 22 V_rms for these two sets of devices. A 12 pl droplet can be split into two 6 pl daughter droplets at 18.7 V_rms with 33 μm electrode devices. Droplet manipulation is also demonstrated with

SUBMITTER: Lin YY 

PROVIDER: S-EPMC3613134 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature