Effect of gene, environment and maternal depressive symptoms on pre-adolescence behavior problems - a longitudinal study.

ABSTRACT:

Background

Depression is a common and disabling condition with a high relapse frequency. Maternal mental health problems and experience of traumatic life events are known to increase the risk of behavior problems in children. Recently, genetic factors, in particular gene-by-environment interaction models, have been implicated to explain depressive etiology. However, results are inconclusive.

Methods

Study participants were members of the SESBiC-study. A total of 889 mothers and their children were followed during the child's age of 3 months to 12 years. Information on maternal depressive symptoms was gathered postpartum and at a 12 year follow-up. Mothers reported on child behavior and traumatic life events experienced by the child at age 12. Saliva samples were obtained fro

SUBMITTER: Agnafors S 

PROVIDER: S-EPMC3615948 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature