Differentially expressed genes during contrasting growth stages of Artemisia annua for artemisinin content.

ABSTRACT: Artemisia annua is the source of antimalarial phytomolecule, artemisinin. It is mainly produced and stored in the glandular secretory trichomes present in the leaves of the plant. Since, the artemisinin biosynthesis steps are yet to be worked out, in this investigation a microarray chip was strategized for the first time to shortlist the differentially expressing genes at a stage of plant producing highest artemisinin compared to the stage with no artemisinin. As the target of this study was to analyze differential gene expression associated with contrasting artemisinin content in planta and a genotype having zero/negligible artemisinin content was unavailable, it was decided to compare different stages of the same genotype with contrasting artemisinin content (seedling--negligible artemis

SUBMITTER: Nair P 

PROVIDER: S-EPMC3616052 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature