Multiple active centers of multi-subunit RNA polymerases.

ABSTRACT: The active center of multi-subunit RNA polymerase consists of two modules, the Mg(2+) module, holding the catalytic Mg(2+) ion, and a module made of a flexible domain, the Trigger Loop. Uniquely, the TL module can be substituted by alternative modules, thus changing the catalytic properties of the active center.

SUBMITTER: Yuzenkova Y 

PROVIDER: S-EPMC3616080 | biostudies-literature | 2012 May-Jun

REPOSITORIES: biostudies-literature