Modified-orientation log to assess hepatic encephalopathy.

ABSTRACT:

Background

The subjectivity of the West-Haven criteria (WHC) hinders hepatic encephalopathy (HE) evaluation. The new HE classification has emphasised assessment of orientation. The modified-orientation log (MO-log, eight questions, scores 0-24; 24 normal) is adapted from a validated brain injury measure.

Aim

To validate MO-log for HE assessment in cirrhosis.

Methods

Cirrhotics admitted with/without HE were administered MO-log. We collected cirrhosis/HE details, admission/daily MO-logs and WHC (performed by different examiners), time to reach normal mentation (MO-log ≥23) and MO-log/WHC change (Δ) over day 1. Outcomes were in-hospital mortality, duration to normal mentation and length-of-stay (LOS). Regressions were performed for each outcome. MO-log inter-rater reliab

SUBMITTER: Salam M 

PROVIDER: S-EPMC3616137 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature