The clinical, serological and molecular diagnosis of emerging dengue infection at a tertiary care institute in southern, India.

ABSTRACT:

Introduction

Dengue is an acute viral infection which presents as uneventful pyrexia to a fatal complication. This infection is increasingly being recognized as the world's major emerging tropical disease and an important public health problem. This article highlights the clinical manifestations of Dengue virus infection and the various molecular tests that were used for its laboratory diagnosis.

Methods

Serum samples from 713 suspected cases of Dengue were collected between August and December 2007. The clinical profiles of 123 hospitalized patients were analyzed. Serology, RT- PCR, virus isolation and sequencing were done.

Results

The most common clinical symptoms were fever, thrombocytopenia, rash and elevated liver enzymes. The demonstration of the Dengue RNA in 5

SUBMITTER: Neeraja M 

PROVIDER: S-EPMC3616556 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature