Polyaspartic acid coated manganese oxide nanoparticles for efficient liver MRI.

ABSTRACT: We report in this communication a simple, facile surface modification strategy to transfer hydrophobic manganese oxide nanoparticles (MONPs) into water by using polyaspartic acid (PASP). We systematically investigated the effect of the size of PASP-MONPs on MRI of normal liver and found that the particles with a core size of 10 nm exhibited greater enhancement than those with larger core sizes.

SUBMITTER: Xing R 

PROVIDER: S-EPMC3617494 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature