Short-term psychological impact of the BRCA1/2 test result in women with breast cancer according to their perceived probability of genetic predisposition to cancer.

ABSTRACT:

Background

The effect of BRCA1/2 gene test result on anxiety, depression, cancer-related thought intrusion or avoidance and perceived control over cancer risk was assessed in breast cancer (BC) patients, according to their perceived probability of genetic predisposition to cancer.

Methods

Two hundred and forty-three (89% response rate) women with BC completed questionnaires after an initial genetic counselling visit (T1), of which 180 (66%) completed questionnaires again after receiving the BRCA1/2 results (T2). The discrepancy between women's perceived probability of cancer genetic predisposition at T1 and the geneticist's computed estimates was assessed.

Results

In all, 74% of women received a negative uninformative (NU), 11% a positive BRCA1/2 and 15% an unclassifi

SUBMITTER: Bredart A 

PROVIDER: S-EPMC3619058 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature