Hyperthermia-induced disruption of functional connectivity in the human brain network.

ABSTRACT:

Background

Passive hyperthermia is a potential risk factor to human cognitive performance and work behavior in many extreme work environments. Previous studies have demonstrated significant effects of passive hyperthermia on human cognitive performance and work behavior. However, there is a lack of a clear understanding of the exact affected brain regions and inter-regional connectivities.

Methodology and principal findings

We simulated 1 hour environmental heat exposure to thirty-six participants under two environmental temperature conditions (25 °C and 50 °C), and collected resting-state functional brain activity. The functional connectivities with a preselected region of interest (ROI) in the posterior cingulate cortex and precuneus (PCC/PCu), furthermore, inter-regional

SUBMITTER: Sun G 

PROVIDER: S-EPMC3620175 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature