Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome.

ABSTRACT:

Background

Few European studies have investigated the effects of long-term exposure to both fine particulate matter (≤ 2.5 µm; PM2.5) and nitrogen dioxide (NO2) on mortality.

Objectives

We studied the association of exposure to NO2, PM2.5, and traffic indicators on cause-specific mortality to evaluate the form of the concentration-response relationship.

Methods

We analyzed a population-based cohort enrolled at the 2001 Italian census with 9 years of follow-up. We selected all 1,265,058 subjects ≥ 30 years of age who had been living in Rome for at least 5 years at baseline. Residential exposures included annual NO2 (from a land use regression model) and annual PM2.5 (from a Eulerian dispersion model), as well as distance to roads with > 10,000 vehicles/day and traffic

SUBMITTER: Cesaroni G 

PROVIDER: S-EPMC3621202 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature