Highly automatic quantification of myocardial oedema in patients with acute myocardial infarction using bright blood T2-weighted CMR.

ABSTRACT:

Background

T2-weighted cardiovascular magnetic resonance (CMR) is clinically-useful for imaging the ischemic area-at-risk and amount of salvageable myocardium in patients with acute myocardial infarction (MI). However, to date, quantification of oedema is user-defined and potentially subjective.

Methods

We describe a highly automatic framework for quantifying myocardial oedema from bright blood T2-weighted CMR in patients with acute MI. Our approach retains user input (i.e. clinical judgment) to confirm the presence of oedema on an image which is then subjected to an automatic analysis. The new method was tested on 25 consecutive acute MI patients who had a CMR within 48 hours of hospital admission. Left ventricular wall boundaries were delineated automatically by variationa

SUBMITTER: Gao H 

PROVIDER: S-EPMC3621376 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature