The cost effectiveness of pandemic influenza interventions: a pandemic severity based analysis.

ABSTRACT:

Background

The impact of a newly emerged influenza pandemic will depend on its transmissibility and severity. Understanding how these pandemic features impact on the effectiveness and cost effectiveness of alternative intervention strategies is important for pandemic planning.

Methods

A cost effectiveness analysis of a comprehensive range of social distancing and antiviral drug strategies intended to mitigate a future pandemic was conducted using a simulation model of a community of ∼30,000 in Australia. Six pandemic severity categories were defined based on case fatality ratio (CFR), using data from the 2009/2010 pandemic to relate hospitalisation rates to CFR.

Results

Intervention strategies combining school closure with antiviral treatment and prophylaxis are the m

SUBMITTER: Milne GJ 

PROVIDER: S-EPMC3621766 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature