Gastrointestinal adverse effects of short-term aspirin use: a meta-analysis of published randomized controlled trials.

ABSTRACT:

Background and objectives

Aspirin is widely used for short-term treatment of pain, fever or colds, but there are only limited data regarding the safety of this use. To summarize the available data on this topic, we conducted a meta-analysis of the published clinical trial literature regarding the gastrointestinal adverse effects of short-term use of aspirin in comparison with placebo and other medications commonly used for the same purpose.

Data sources and methods

An extensive literature search identified 119,310 articles regarding possible adverse effects of aspirin, among which 23,131 appeared to possibly include relevant data. An automated text-mining procedure was used to score the references for potential relevance for the meta-analysis. The 3,983 highest-scoring artic

SUBMITTER: Baron JA 

PROVIDER: S-EPMC3627011 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature