A natural fiber complex reduces body weight in the overweight and obese: a double-blind, randomized, placebo-controlled study.

ABSTRACT:

Objective

A proprietary natural fiber complex (Litramine IQP G-002AS) derived from Opuntia ficus-indica, and standardized on lipophilic activity, was previously shown in preclinical and human studies to reduce dietary fat absorption through gastrointestinal (GI) fat binding. Here, we investigated the efficacy and safety of IQP G-002AS in body weight reduction.

Design and methods

One hundred twenty-five overweight and obese adults participated in the study. Subjects were advised on physical activity, and received nutritional counseling, including hypocaloric diet plans (30% energy from fat and 500 kcal deficit/day). After a 2-week placebo run-in phase, subjects were randomized to receive either 3 g/day of IQP G-002AS (IQ) or a placebo. The primary endpoint was change in body

SUBMITTER: Grube B 

PROVIDER: S-EPMC3627296 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature