Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort.

ABSTRACT:

Background

Plant-based and fiber-rich diets high in vegetables, fruit, and whole grains are recommended to prevent cancer and chronic conditions associated with renal cell carcinoma (RCC), such as obesity, hypertension, and diabetes. Diet may play a role in the etiology of RCC directly and/or indirectly.

Objective

In a large prospective cohort of US men and women, we comprehensively investigated dietary intake and food sources of fiber in relation to RCC risk.

Design

Participants of the NIH-AARP Diet and Health Study (n = 491,841) completed a self-administered questionnaire of demographics, diet, lifestyle, and medical history. Over 9 (mean) years of follow-up we identified 1816 incident cases of RCC. HRs and 95% CIs were estimated within quintiles by using multivaria

SUBMITTER: Daniel CR 

PROVIDER: S-EPMC3628376 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature