Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis.

ABSTRACT:

Background

Bacterial vaginosis (BV) is a polymicrobial syndrome characterized by a change in vaginal flora away from predominantly Lactobacillus species. The cause of BV is unknown, but the condition has been implicated in diverse medical outcomes. The bacterium Atopobium vaginae has been recognized only recently. It is not readily identified by commercial diagnostic kits. Its clinical significance is unknown but it has recently been isolated from a tuboovarian abcess.

Methods

Nucleotide sequencing of PCR amplified 16S rRNA gene segments, that were separated into bands within lanes on polyacrylamide gels by denaturing gradient gel electrophoresis (DGGE), was used to examine bacterial vaginal flora in 46 patients clinically described as having normal (Lactobacillus spp. predo

SUBMITTER: Ferris MJ 

PROVIDER: S-EPMC362875 | biostudies-literature | 2004 Feb

REPOSITORIES: biostudies-literature