Dual African origins of global Aedes aegypti s.l. populations revealed by mitochondrial DNA.

ABSTRACT:

Background

Aedes aegypti is the primary global vector to humans of yellow fever and dengue flaviviruses. Over the past 50 years, many population genetic studies have documented large genetic differences among global populations of this species. These studies initially used morphological polymorphisms, followed later by allozymes, and most recently various molecular genetic markers including microsatellites and mitochondrial markers. In particular, since 2000, fourteen publications and four unpublished datasets have used sequence data from the NADH dehydrogenase subunit 4 mitochondrial gene to compare Ae. aegypti collections and collectively 95 unique mtDNA haplotypes have been found. Phylogenetic analyses in these many studies consistently resolved two clades but no comprehensive s

SUBMITTER: Moore M 

PROVIDER: S-EPMC3630099 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature