The relationship between EQ-5D, HAQ and pain in patients with rheumatoid arthritis.

ABSTRACT:

Objective

This study aims to provide robust estimates of EQ-5D as a function of the HAQ and pain in patients with RA.

Method

Repeated observations were made of patients diagnosed with RA in a US observational cohort (n = 100 398 observations) who provided data on HAQ, pain on a visual analogue scale and the EQ-5D questionnaire. We used a bespoke statistical method based on mixture modelling to appropriately reflect the characteristics of the EQ-5D instrument and to compare this with results from standard multiple regression.

Results

EQ-5D can be predicted from summary HAQ and pain scores. We identify four different classes of respondents who differ in terms of disease severity. Unlike the multiple regression, the mixture model exhibits very good fit to the data and do

SUBMITTER: Hernandez Alava M 

PROVIDER: S-EPMC3630395 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature