Unisensory processing and multisensory integration in schizophrenia: a high-density electrical mapping study.

ABSTRACT: In real-world settings, information from multiple sensory modalities is combined to form a complete, behaviorally salient percept - a process known as multisensory integration. While deficits in auditory and visual processing are often observed in schizophrenia, little is known about how multisensory integration is affected by the disorder. The present study examined auditory, visual, and combined audio-visual processing in schizophrenia patients using high-density electrical mapping. An ecologically relevant task was used to compare unisensory and multisensory evoked potentials from schizophrenia patients to potentials from healthy normal volunteers. Analysis of unisensory responses revealed a large decrease in the N100 component of the auditory-evoked potential, as well as early differen

SUBMITTER: Stone DB 

PROVIDER: S-EPMC3632320 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature