Ontology highlight
ABSTRACT:
SUBMITTER: Turnbull C
PROVIDER: S-EPMC3632836 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Nature genetics 20100509 6
Breast cancer is the most common cancer in women in developed countries. To identify common breast cancer susceptibility alleles, we conducted a genome-wide association study in which 582,886 SNPs were genotyped in 3,659 cases with a family history of the disease and 4,897 controls. Promising associations were evaluated in a second stage, comprising 12,576 cases and 12,223 controls. We identified five new susceptibility loci, on chromosomes 9, 10 and 11 (P = 4.6 x 10(-7) to P = 3.2 x 10(-15)). W ...[more]