Unknown

Dataset Information

0

Airway smooth muscle in the pathophysiology and treatment of asthma.

ABSTRACT: Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is potentiated by constrictor hyperresponsiveness, impaired relaxation and length adaptation. ASM also contributes to airway remodeling and inflammation in asthma. In light of this, ASM is an important target in the treatment of asthma.

SUBMITTER: Doeing DC 

PROVIDER: S-EPMC3633438 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Airway smooth muscle in the pathophysiology and treatment of asthma.

Doeing Diana C DC   Solway Julian J  

Journal of applied physiology (Bethesda, Md. : 1985) 20130110 7

Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is potentiated by constrictor hyperresponsiveness, impaired relaxation and length adaptation. ASM also contributes to airway remodeling and inflammation in asthma. In light of this, ASM is an important target in the treatment of asthma. ...[more]

Similar Datasets

Unknown Bitter Taste Receptors: Taking a Bigger Bite of Airway Smooth Muscle Pathophysiology.
| S-EPMC6503616 | biostudies-literature
Transcriptomics Fatal Asthma and Non-Asthma Donor-Derived Airway Smooth Muscle Transcriptome Response to Glucocorticoid Treatment
2018-12-31 | GSE94335 | GEO
Unknown Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction.
| S-EPMC3545777 | biostudies-literature
Unknown Does airway smooth muscle express an inflammatory phenotype in asthma?
| S-EPMC3085869 | biostudies-other
Unknown Suppression of Eosinophil Integrins Prevents Remodeling of Airway Smooth Muscle in Asthma.
| S-EPMC5220051 | biostudies-literature
Unknown A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma.
| S-EPMC5318459 | biostudies-literature
Unknown Dabigatran ameliorates airway smooth muscle remodeling in asthma by modulating Yes-associated protein.
| S-EPMC7348141 | biostudies-literature
Unknown Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma.
| S-EPMC4514847 | biostudies-literature
Unknown Antigen-specific CD4+ T cells drive airway smooth muscle remodeling in experimental asthma.
| S-EPMC1088014 | biostudies-literature
Unknown Endobronchial Ultrasound Reliably Quantifies Airway Smooth Muscle Remodeling in an Equine Asthma Model.
| S-EPMC4562526 | biostudies-literature