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In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide.


ABSTRACT: Polystyrene nanoparticles stained with squaraine catenane endoperoxide exhibit remarkably high chemiluminescence and enable optical imaging of biodistribution in living mice. Whole-body chemiluminescence imaging was much more effective than fluorescence at identifying lung accumulation of the nanoparticles.

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC3633569 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature