Relationship between sex hormones and cognitive performance in men with substance use.

ABSTRACT:

Background

Hypogonadism is common with opiate-like drug use and may contribute to cognitive abnormalities. With the increasing epidemic of HIV and substance use (SU) worldwide, it is important to understand the impact of these conditions on cognition, which may affect quality of life and possibly decrease adherence to treatment. We hypothesized that men with SU, by virtue of hypogonadism secondary to HIV and/or SU, may demonstrate impaired cognition.

Methods

We recruited men aged 18-50 from a population of low income, inner-city individuals. Details of HIV and SU status, serum blood levels of total testosterone (TT), free testosterone (FT) and estradiol (E2) were assessed. All subjects were administered ten neuropsychological tests.

Results

Our sample consisted of 68

SUBMITTER: Zilbermint MF 

PROVIDER: S-EPMC3637021 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature