Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria.

ABSTRACT:

Background

Drug resistance to anti-malarial compounds remains a serious problem, with resistance to newer pharmaceuticals developing at an alarming rate. The development of new anti-malarials remains a priority, and the rational selection of putative targets is a key element of this process. Discovery-2 is an update of the original Discovery in silico resource for the rational selection of putative drug target proteins, enabling researchers to obtain information for a protein which may be useful for the selection of putative drug targets, and to perform advanced filtering of proteins encoded by the malaria genome based on a series of molecular properties.

Methods

An updated in silico resource has been developed where researchers are able to mine information on malaria protei

SUBMITTER: Mpangase PT 

PROVIDER: S-EPMC3637051 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature