Vaccination strategies for future influenza pandemics: a severity-based cost effectiveness analysis.

ABSTRACT:

Background

A critical issue in planning pandemic influenza mitigation strategies is the delay between the arrival of the pandemic in a community and the availability of an effective vaccine. The likely scenario, born out in the 2009 pandemic, is that a newly emerged influenza pandemic will have spread to most parts of the world before a vaccine matched to the pandemic strain is produced. For a severe pandemic, additional rapidly activated intervention measures will be required if high mortality rates are to be avoided.

Methods

A simulation modelling study was conducted to examine the effectiveness and cost effectiveness of plausible combinations of social distancing, antiviral and vaccination interventions, assuming a delay of 6-months between arrival of an influenza pandemi

SUBMITTER: Kelso JK 

PROVIDER: S-EPMC3637125 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature